红车轴草中(6aR,11aR)-三叶豆紫檀苷对马铃薯腐烂茎线虫的麻醉活性研究

天然产物研究与开发 ›› 2011, Vol. 23 ›› Issue (5): 820-823.

红车轴草中(6aR,11aR)-三叶豆紫檀苷对马铃薯腐烂茎线虫的麻醉活性研究

徐蕊1，金辉1，刘权1，燕志强1，崔海燕1，秦波1,2*

1中国科学院兰州化学物理研究所中国科学院西北特色植物资源化学重点实验室甘肃省天然药物重点实验室；2兰州大学功能有机分子化学国家重点实验室，兰州 730000

收稿日期:2010-09-30 出版日期:2011-10-25 发布日期:2011-09-26
基金资助:
国家自然科学基金（31070386,21102154）；中科院兰州化物所优秀人才计划项目（080423SYR1）；甘肃省科技支撑计划-社会发展类项目（1011FKCA128）

Anesthetic Activity of (6aR,11aR)-Trifolirhizin from Trifolium pratense to Ditylenchus destructor

XU Rui1,JIN Hui1,LIU Quan1,YAN Zhi-qiang1,CUI Hai-yan1,QIN Bo1,2*

1Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000; 2State Key Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000

Received:2010-09-30 Online:2011-10-25 Published:2011-09-26

摘要/Abstract

摘要： 从红车轴草（Trifolium pratense L.）根乙醇提取物中分离得到了黄酮苷类化合物(6aR,11aR)-三叶豆紫檀苷，并运用核磁共振波谱学技术鉴定了其化学结构。采用实验室活体生物试验方法，研究了(6aR,11aR)-三叶豆紫檀苷对马铃薯腐烂茎线虫的麻醉活性。结果表明，该化合物对马铃薯腐烂茎线虫二龄幼虫有一定的麻醉活性，麻醉作用的强度与其浓度及作用时间密切相关。

关键词: 红车轴草, (6aR,11aR)-三叶豆紫檀苷, 马铃薯腐烂茎线虫, 麻醉活性

Abstract: (6aR,11aR)-Trifolirhizin was isolated and purified from the root extracts of Trifolium pratense and structurally characterized mainly by NMR spectra.Its anesthetic activity was tested by bioassay methods with the juvenile stage 2 (J2) nematodes.The results showed that (6aR,11aR)-trifolirhizin had anesthetic effect on Ditylenchus destructor,and the anesthetic activity had close relationship with its treated concentrations and time.

Key words: Trifolium pratense L, (6aR,11aR)-Trifolirhizin, Ditylenchus destructor, anesthetic activity

中图分类号:

Q949.96

徐蕊，金辉，刘权，燕志强，崔海燕，秦波. 红车轴草中(6aR,11aR)-三叶豆紫檀苷对马铃薯腐烂茎线虫的麻醉活性研究[J]. 天然产物研究与开发, 2011, 23(5): 820-823.

XU Rui,JIN Hui,LIU Quan,YAN Zhi-qiang,CUI Hai-yan,QIN Bo. Anesthetic Activity of (6aR,11aR)-Trifolirhizin from Trifolium pratense to Ditylenchus destructor[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(5): 820-823.