天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (6): 822-824.

• 研究论文 • 上一篇    下一篇

反柄紫芝中的二个新化合物(补充数据)

秦付营1,2,戴伟锋2,3,程永现1,2*   

  1. 1 河南中医药大学,郑州 450008;2 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;3 昆明理工大学生命科学与技术学院,昆明 650500
  • 出版日期:2016-06-30 发布日期:2017-01-17

Two New Compounds from Ganoderma cochlear

QIN Fu-ying1,2,DAI Wei-feng2,3,CHENG Yong-xian1,2*   

  1. 1 Henan University of Traditional Chinese Medicine.Zhengzhou 450008,China; 2 State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences.Kunming 650201,China; 3 Faculty of Life Science and Technology, Kunming University of Science and Technology,Kunming 650500,China
  • Online:2016-06-30 Published:2017-01-17

摘要: 采用色谱法从反柄紫芝的子实体中分离得到4个化合物,波谱学方法鉴定了它们的结构,分别为: cochlearol E(1)、cochlearol F(2)、ganocin A(3)和ganocin B(4)。其中化合物1和2是新化合物,化合物3和4系文献已报道的源自本菌子实体的多环芳香杂萜。化合物1、3和4均是外消旋体,对新化合物1进行了手性拆分并通过量子化学计算方法确定了其对映体的绝对构型。

关键词: 反柄紫芝, 灵芝科, 杂萜, 外消旋体, 绝对构型

Abstract: Two new meroterpenoids,termed cochlearols E (1) and F (2),along with two known meroterpenoids,ganocins A (3) and B (4) were isolated from the fruiting bodies of Ganoderma cochlear. The structures of the new compounds were identified on the basis of spectroscopic methods.In particular,compounds 1,3 and 4 were isolated as racemic mixtures,chiral separation of 1 followed by computational methods assigned its absolute configuration.

Key words: Ganoderma cochlear, Ganodermataceae, meroterpenoids, racemates, absolute configuration

中图分类号:  R93