肋果茶中的萜类化学成分研究

doi:A

天然产物研究与开发 ›› 2012, Vol. 23 ›› Issue (7): 869-.doi: A

肋果茶中的萜类化学成分研究

张兰春^1,2，吴兴德²，何隽²，彭丽艳²，张荣平^1*，赵勤实^2*

¹昆明医学院药学院，昆明 650500；²中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室，昆明 650204

出版日期:2012-08-04 发布日期:2012-08-27

Terpenoids from Sladenia celastrifolia

ZHANG Lan-chun1, 2, WU Xing-de2, HE Juan2, PENG Li-yan2, ZHANG Rong-ping1*, ZHAO Qin-shi2*

¹College of Pharmacology, Kunming Medical University, Kunming 650500, China; ²State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China

Online:2012-08-04 Published:2012-08-27
Supported by:
National key Basic Research Program (973)sub-project (Nos.2009CB522303 and 2011CB915503)

摘要/Abstract

摘要： 从肋果茶（Sladenia celastrifolia）95%乙醇提取物的乙酸乙酯部位中分离得到15个萜类化合物，经波谱学方法分别鉴定为sladeniafolin A (1), grasshopper ketone (2), (3S,5R,6S,7E,9R)-7-megastigmene-3,6,9-triol (3), hedytriol (4), (3S,5R,6R,7E,9R) -3,5,6,9-tetrahydroxy-7-megastigmene (5), 1′S*,4′R*-8-(4′-hydroxy-2′,6′,6′-trimethylcyclohex-2-enyl) -6-methyloct-3E,5E,7E-trien -2-one (6), 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid (7), 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid (8), pomolic acid (9), 3-O-acetyl pomolic acid (10), ursaldehyde (11), camarolide (12), 3β-hydroxyurs-11-en-13β(28)-olide (13), 3β-hydroxy -11α,12α-epoxy-urs-13β,28-olide (14) 和28-O-β-D-glucopyranosyl euscaphic acid (15)。以上化合物均首次从该植物中分离得到，其中1为新的C9裂环烯醚萜。

关键词: 肋果茶, 裂环烯醚萜, 倍半萜, 三萜

Abstract: A new C9 seco-iridoid sladeniafolin A (1), together with fourteen known compounds were isolated from the ethanol extract of Sladenia celastrifolia Kurz for the first time. On the basis of spectral data, the known compounds were identified as grasshopper ketone (2), (3S,5R,6S,7E,9R)-7-megastigmene-3,6,9-triol (3), hedytriol (4), (3S,5R,6R,7E,9R)-3,5,6,9-tetrahydroxy-7-megastigmene (5), 1′S*,4′R*-8-(4′-hydroxy-2′,6′,6′-trimethylcyclohex-2-enyl)-6-methyloct-3E,5E,7E-trien-2-one (6), 2α,3α,19α,23-tetrahydroxyurs-12-en -28-oic acid (7), 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid (8), pomolic acid (9), 3-O-acetyl pomolic acid (10), ursaldehyde (11), camarolide (12), 3β-hydroxyurs-11-en-13β(28)-olide (13), 3β-hydroxy-11α,12α-epoxy-urs-13β,28-olide (14) and 28-O-β-D- glucopyranosyl euscaphic acid (15) .

Key words: Sladenia celastrifolia, seco-iridoid, sesquiterpenoid, triterpenoid

中图分类号:

R284.2 Q946.91

张兰春，吴兴德，何隽，彭丽艳，张荣平，赵勤实. 肋果茶中的萜类化学成分研究[J]. 天然产物研究与开发, 2012, 23(7): 869-.

ZHANG Lan-chun, WU Xing-de, HE Juan, PENG Li-yan, ZHANG Rong-ping, ZHAO Qin-shi. Terpenoids from Sladenia celastrifolia[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(7): 869-.

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肋果茶中的萜类化学成分研究

Terpenoids from Sladenia celastrifolia

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