天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (增刊1): 178-184.doi: 10.16333/j.1001-6880.2018.S.033

• 综述 • 上一篇    下一篇

桐花树及其内生菌的化学成分与生物活性研究进展

江蕾1,2,3,易湘茜1,徐谱1,3,周桂2*,高程海1*   

  1. 1广西中医药大学海洋药物研究所 广西中药药效研究重点实验室,南宁 530200;2广西民族大学 海洋与生物技术学院 广西高校微生物与植物资源利用重点实验室,南宁 530006;3广西科学院 广西海洋天然产物与组合生物合成化学重点实验室培育基地,南宁 530007
  • 出版日期:2018-07-31 发布日期:2018-07-31
  • 基金资助:

    国家自然科学基金(21662006);广西自然科学基金(2015GXNSFBA139195);广西高校科学技术研究重点项目(ZD2014041);广西中药药效研究重点实验室项目(17-259-20-K2).

Chemical Constituents and Biological Activities of Mangrove Aegiceras Corniculatum and Endophytic Microorganism

JIANG Lei 1,2,3, YI Xiang-xi1, XU Pu 1,3, ZHOU Gui 2*, GAO Cheng-hai1*   

  1. 1Guangxi University of Chinese Medicine,Institute of Marine Drugs/ Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica,Nanning,530200,China; 2School of Marine Sciences and Biotechnology,Guangxi University for Nationalities/Guangxi Colleges and Universities Key
    Laboratory of Utilization of Microbial and Botanical Resources,Nanning 530006,China; 3Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynethesis Chemistry,Guangxi Academy of Sciences,Nanning 530007,China
  • Online:2018-07-31 Published:2018-07-31

摘要: 桐花树(Aegiceras Cornicnlatnm)为真红树植物,其内生菌物种多样性丰富。目前已经从桐花树及其内生菌发酵提取物中获得105个化合物,类型包括萜类、醌类、甾醇类、有机酸、黄酮类等,其中包括25个新化合物,醌类化合物居多。桐花树化学成分的主要生理生化活性有抗菌、抗氧化、抗衰老、抗肿瘤等。本文综述了过去60年来国内外学者从桐花树及其内生菌中发现的化学成分及其生物活性,为红树植物桐花树今后的天然产物化学研究与开发提供科学依据和理论基础。

关键词: 桐花树, 红树, 化学成分, 生物活性, 内生菌

Abstract: Aegiceras corniculatum was a true mangrove plant and riched in endophytic microorganisms.So far,105 compounds were reported that isolated from A.Corniculatum and its endophytic microorganism’s fermentations,which exhibited biological activities such as antibacterial,antioxidant,anti-aging and antitumor.25 compounds were identified as new compounds and quinones were predominant.This paper reviewed the chemical constituents and biological activities have been found in recent 60 years,which could provide scientific and theoretical basis for the study and develop of natural products of medicinal value.

Key words: Aegiceras Cornicnlatnm, mangrove, chemical constituents, biological activities, endophytic microorganism

中图分类号: 

O629.9