Research Progress in Natural α-Glucosidase/Amylase Inhibitors Classified in the Family of C7N Aminocyclitols

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Abstract

Abstract: The C₇N aminocyclitol family is a relatively new class of natural products that is increasingly gaining recognition due to their significant biomedical and agricultural uses. These secondary metabolites are exclusively produced by microorganisms, particularly soil bacteria of the order of Actinomycetes. Their chemical structures most commonly contain an unsaturated aminocyclitol moiety, valienamine, which is known to be responsible for their biological activities. Among the C₇N aminocyclitol family, most members act as α-glucosidase/amylase inhibitors. This review covers the discovery, structure determinations, and biological properties of α-glucosidase/amylase inhibitors classified in the family of C₇N aminocyclitols, including the researches performed by the author of this article.

Key words: C₇N aminocyclitol, α-glucosidase/amylase inhibitor, Actinomycetes

CLC Number:

TQ464.4

GENG Peng, BAI Gang. Research Progress in Natural α-Glucosidase/Amylase Inhibitors Classified in the Family of C₇N Aminocyclitols[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(6): 848-.

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Research Progress in Natural α-Glucosidase/Amylase Inhibitors Classified in the Family of C₇N Aminocyclitols

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