Isolation,Identification and Antimicrobial Activity of Secondary Metabolites from a Soil-derived Streptomyces from Arid Habitats of Qinghai

doi:10.16333/j.1001-6880.2015.11.012

Abstract

Abstract: Five compounds, N-acetyramine (1), N-acetyltryptamine (2),pyrrole-2-carboxamide (3),inthomycin C (4) and inthomycin B (5),were isolated from the fermentation broth of Streptomyces pactum KIB-HL8,and their structures were elucidated by analysis of NMR and MS data.In addition,compound 4 moderately inhibited growth of Staphylococcus aureus. Compounds 1 and 2 showed significant antifungal activity against Botrytis cinerea. Compound 3 displayed inhibitory activity against Alternaria solani.

Key words: Streptomyces, secondary metabolites, isolation and identification, antibacterial activity, antifungal activity

CLC Number:

YU Zhi-yin1,2, YU Ming-ming2, LUO Jian-ying2, SU Can2, XUE Quan-hong3, HUANG Sheng-xiong2, SUN Yun1*, MA Ya-tuan 2,3*. Isolation,Identification and Antimicrobial Activity of Secondary Metabolites from a Soil-derived Streptomyces from Arid Habitats of Qinghai[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2015, 27(11): 1900-1904.

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Isolation,Identification and Antimicrobial Activity of Secondary Metabolites from a Soil-derived Streptomyces from Arid Habitats of Qinghai

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