Abstract: The chemical constituents of the n-butanol extractive of the mycelium of Penicillium jiangxiense, the anamorph of medicinal Cordyceps jiangxiensis, were separated and purified by various chromatographic techniques. Six compounds were obtained and their structures were elucidated on the basis of spectral analysis as uracil (1), 2′-deoxyuridine (2), adenine (3), adenosine (4), methyl L-pyroglutamate (5), 2′-O-methyladenosine (6), of which compounds 2, 5 and 6 were isolated from Cordyceps species for the first time.

Key words: Penicillium jiangxiense, secondary metabolites, purification, structural identification