Chemical Constituents from Inula helianthus-aquatica

doi:A

Abstract

Abstract: Twenty-four compounds were isolated from the aerial parts of Inula helianthus-aquatica. On the basis of spectral data, their structures were identified as aromaticin (1), 8-epi-helenalin (2), bigelovin (3), 2,3-dihydroaromaticin (4), carpesiolin (5), ergolide (6), inuchinenolide C (7), 6α-acetoxy-isoinuviscolide (8), 8-epi-inuviscolide (9), inuchinenolide B (10), tomentosin (11), 11α,13-dihydrotomentosin (12), inuchinenolide A (13), 4H-tomentosin (14), 11β,13-dihydro-4H-tomentosin (15), 11-epi-sundiversifolide (16), sundiversifolide (17), 8,9,10-trihydroxythymol (18), 10-hydroxy-8,9-dioxyisopropylidenethymol (19), 8,10-dihydroxy- 9-isobutyryloxythymol (20), 8-hydroxy-9,10-diisobutyryloxythymol (21), 8-hydroxy-9- isobutyryloxy-10-(2-methylbutanoyl)thymol (22), 8,9-epoxy-3,10-diisobutyryloxythymol (23), and 8,9-epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol (24). All the compounds except 1-6 were isolated from this plant for the first time.

Key words: Inula, Inula helianthus-aquatica, sesquiterpene, monoterpenes

CLC Number:

CHANG Rui-jie, QIN Jiang-jiang, CHENG Xiang-rong, JIN Hui-zi, ZHANG Wei-dong. Chemical Constituents from Inula helianthus-aquatica[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(3): 291-297.

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