天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (12): 2084-2089.doi: 10.16333/j.1001-6880.2015.12.017

• 研究简报 • 上一篇    下一篇

马兰重金属元素ICP-MS及主成分聚类分析

王国凯,郑娟,郁阳,刘劲松,王诤,蔡百祥,王刚*   

  1. 安徽中医药大学药学院现代中药安徽省重点实验室,合肥 230012
  • 出版日期:2015-12-29 发布日期:2016-01-06

Determination and Evaluation of Heavy Metal Elements in Kalimeris indica by ICP-MS Coupled with Principal Component Analysis and Cluster Analysis

WANG Guo-kai, ZHENG Juan, YU Yang, LIU Jin-song, WANG Zheng, CAI Bai-xiang, WANG Gang*   

  1. School of Pharmacy,Anhui University of Chinese Medicine & Anhui Key Laboratory for modern Chinese Materia Medica,Hefei 230012,China
  • Online:2015-12-29 Published:2016-01-06

摘要: 采用微波消解-ICP-MS法测定不同产地马兰重金属元素的含量,并运用主成分分析法和聚类分析法对含量进行分析和评价。主成分分析提取2个因子,对15批次马兰进行综合评价,其综合评价函数为F=0.586F1+0.414F2,结果亳州药材市场、亳州2以及宣城市马兰样品综合得分排名前三。聚类分析说明含量存在产地相似性。结果说明ICP-MS法快速、灵敏、准确,可作为马兰中重金属元素含量分析方法,并为马兰的质量控制与安全评价提供参考依据。

关键词: 马兰, 重金属元素, 主成分分析, 聚类分析

Abstract: A microwave digestion coupled with inductively coupled plasma-mass spectrometry (ICP-MS) method was established for the determination of heavy metal elements in Kalimeris indica from different habitats.The results were analyzed by principal component analysis and cluster analysis.Two principal factors were extracted and used to comprehensively evaluate heavy metal elements from 15 batches of K.indica. The comprehensive function was F=0.586F1+0.414F2, which resulted in the top three samples coming from Bozhou Chinese medicine market,Bozhou 2 and Xuancheng,respectively.The cluster analysis results showed that the contents of heavy metals were similar by habitats.The study indicated that ICP-MS was a quick,accurate,sensitive method to determine the contents of heavy metal elements in K.indica.

Key words: Kalimeris indica, heavy metal elements, principal component analysis, cluster analysis

中图分类号: 

R284.1