天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (8): 1332-1336.doi: 10.16333/j.1001-6880.2016.8.029

• 综述 • 上一篇    下一篇

甾体皂苷生物合成相关酶及基因研究进展

尹艳1,关红雨2,张夏楠2*   

  1. 1 贵州大学药学院,贵阳 550025;2首都医科大学中医药学院,北京 100069
  • 出版日期:2016-08-30 发布日期:2017-01-17

Review on Enzymes and Genes Related to the Biosynthesis of Steroidal Saponins

YIN Yan1,GUAN Hong-yu2,ZHANG Xia-nan2*   

  1. 1 School of Pharmaceutical Sciences,Guizhou University,Guiyang 550025,China; 2School of Traditional Chinese Medicine,Capital Medical University,Beijing 100069,China
  • Online:2016-08-30 Published:2017-01-17

摘要: 甾体皂苷是植物中广泛存在的一种次生代谢产物,其种类繁多且大多数有很强的生理活性,具有很大的药用研究价值和广泛应用前景。甾体皂苷生物合成途径复杂,受到多种酶的调控。本文综述了植物甾体皂苷的生物合成途径及途径中关键酶及基因的研究进展,并对其研究前景做简要展望。

关键词: 甾体皂苷, 生物合成, 环阿屯醇, 糖基转移酶, 糖苷酶

Abstract: Steroidal saponins are a class of secondary metabolites widely existed in plants with strong physiological activity.The biosynthetic pathway of steroidal saponins is complex and regulated by many kinds of enzymes.This paper reviewed the research progress on the biosynthetic pathway of plant steroidal saponins and its key enzymes and genes,and give a brief outlook about the research prospects.

Key words: steroidal saponins, biosynthesis, cycloartenol, glycosyltransferase, glucosidase

中图分类号: 

R932