天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (增刊1): 202-206.doi: 10.16333/j.1001-6880.2017.S.041

• 综述 • 上一篇    下一篇

苦豆子化学成分及药理作用研究进展

卢子滨1,范春林2,周红玲1,禹志领3,陈卫民2,余林中1,刘俊珊1,3*   

  1. 1 南方医科大学中医药学院中药药理教研室;2暨南大学药学院药物化学教研室,广州 510515;3香港浸会大学中医药学院岑尧宽岑碧泉纪念癌症炎症研究中心,香港
  • 出版日期:2017-08-02 发布日期:2017-08-02

Chemical Constituents and Pharmacological Activities of Sophora alopecuroides L.

LU Zi-bin1,FAN Chun-lin2,ZHOU Hong-ling1,YU Zhi-ling3, CHEN Wei-min 2,YU Lin-zhong1,LIU Jun-shan1,3*   

  1. 1 Department of Traditional Chinese Medicine,Southern Medical University;  2 Department of Pharmacy,Jinan University,Guangzhou 510515,China; 3 Shum YiuFoon Shum Bik Chuen Memorial Centre for Cancer and Inflammation Research,Department of Traditional Chinese Medicine,Hong Kong Baptist University, Hong Kong
  • Online:2017-08-02 Published:2017-08-02

摘要: 苦豆子为豆科槐属植物苦豆子(Sophora alopecuroides L.)的干燥全草、根及种子,具有清热解毒、抗菌消炎作用。近年来的研究发现,苦豆子由生物碱、黄酮、挥发油、氨基酸、多糖等构成并具有中枢抑制、抗心律失常、抗炎、抗肿瘤等多种药理活性。本文主要就近年来苦豆子的化学成分及药理作用研究进展作一综述,以期为相关领域研究人员提供有益参考。

关键词: 苦豆子, 化学成分, 药理作用

Abstract: The dry herb,root and seed of Sophora alopecuroides L.have functions in heat-clearing and detoxifying,anti-bacteria and anti-inflammation in traditional Chinese medicine.Recent studies demonstrated that the chemical components of Sophora alopecuroides L.include alkaloids,flavones,volatile oils,amino acids and polysaccharides.Pharmacological research indicated that it exhibits central inhibition,anti-arrhythmic,anti-inflammation,anti-tumor effects.The review mainly summarizes the chemical constituents and pharmacological activities of Sophora alopecuroides L.in recent years.

Key words: Sophora alopecuroides L., chemical Components, pharmacological activities