The extracts of the compound Loki Zupa were eluted with a series of ethanol solutions,and 4 elution sites were separated.The DPPH radical scavenging rate,the OH radical scavenging rate,and the total antioxidant capacity of T-AOC were used as Indexes were used to evaluate the antioxidant activity,and the content of total polyphenols and total flavonoids in different elution parts of the compound Loki Zupa was explored.UHPLC-QE-MS was used to identify the main flavonoids and phenolic acid compounds in the compound Loki Zupa,and the self-built MS database and the corresponding fragmentation law matching method were used to identify the peaks containing MS data.The results showed that the different elution parts of compound Loki Zupa all had antioxidant activity and showed a certain dose-effect relationship.Among them,the 20% ethanol elution part of compound Loki Zupa had stronger antioxidant capacity.The content of total flavonoids in the total polyphenols of compound Loki Zupa is higher,and the total flavonoids content in the 20% ethanol elution part is the highest (276.24 mg/g) in the different elution parts,and the total polyphenol content is the highest in the 40% ethanol elution part (130.5 mg/g).UHPLC-QE-MS analysis of the main chemical components in the compound Loki Zupa,a total of 99 kinds of flavonoids and phenolic acid compounds were detected in the positive and negative ion mode.Through the analysis of the antioxidant activity and chemical components of the Xinjiang anti-asthma compound Loki Zupa.It shows that the compound Loki Zupa has good antioxidant capacity and is rich in flavonoids and phenolic acid compounds.The aim is to provide experimental reference for the research on the material basis of compound Loki Zupa.