Effects of Bombesin on the Growth of Hela and HFL1

doi:10.16333/j.10016880.2016.S.024

NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2016, Vol. 28 ›› Issue (增刊2): 288-290. doi: 10.16333/j.10016880.2016.S.024

• Article • Previous Articles Next Articles

Effects of Bombesin on the Growth of Hela and HFL1

ZHANG Mengtian,XU Bilei,YANG Dongmei*

Jishou University,College of Biological and Environmental Science,Jishou 416000,China

Online:2016-12-31 Published:2017-03-03

Abstract

Abstract: The effect of bombesin on the proliferation of human cervical carcinoma Hela cells was investigated.MTT reduction assay was performed to measure the proliferation of Hela cells and with different concentrations of bombesin.The result showed that the proliferation of HFL1 cells was observed with different concentrations(1501550 μg/mL),in which the 150 μg/mL BBS showed the highest stimulation effect.Suppression of Hela cells was observed with different concentrations(1501550 μg/mL),in which the 750 μg/mL BBS showed the highest suppression effect.Hence,it was concluded that bombesin had the suppressive effects on proliferation of Hela in vitro.

Key words: bombesin, Hela, HFL1

CLC Number:

R7336

ZHANG Mengtian,XU Bilei,YANG Dongmei*. Effects of Bombesin on the Growth of Hela and HFL1[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(增刊2): 288-290.

[1]	HUANG Zhi, LUO Si-yuan, LIU Li, CHEN Tao, DING Chun-bang, FENG Shi-ling. Study on polyphenols,antioxidant and anticancer activities of methanol extract from olive leaves [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(增刊2): 1-6.
[2]	HU Yang-liang, LI Huan, JI Gui-mei, SHEN Xiao-ling, WEI Xiao-yi, FU Lin-chun, HU Ying-jie . Chemical constituents with HDAC inhibitory effects from Epimedium sagittatum [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(10): 1681-1690.
[3]	ZHANG Li-juan, XU Wen-qing, JIANG Cheng-feng, YANG Fu-jun, SHEN Xiu . Synthesis and in vitro* Anti-Tumor Effects of Hydroxytanshinone IIA [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2015, 27(12): 2027-2030.
[4]	CHEN Di-ling1, LONG He-ming2, ZHANG He-ming1, LI Ning1, LIU Song-hao1. In vitro* Antioxidant and Mitochondria Protective Activities of Clerodendranthus spicatus Extracts [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(3): 392-397.
[5]	JIANG Cheng-feng, LI Rui-feng, XU Dan, YANG Fu-jun, SHEN Xiu, XU Wen-qing. Preparation of Tanshinone ⅡA Derivatives and Their Proliferation Inhibitory Activity against HeLa Cells [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(3): 385-388.

Effects of Bombesin on the Growth of Hela and HFL1

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 5

Recommended Articles

Metrics

Comments