天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (1): 120-124.doi: 10.16333/j.1001-6880.2017.1.023

• 开发研究 • 上一篇    下一篇

三七的提取动力学研究

王博然1,2,张文生2,赵万顺2,叶正良3*   

  1. 1天津中医药大学,天津 300193;2天士力制药集团股份有限公司,天津 300410;3天士力控股集团有限公司,天津 300410
  • 出版日期:2017-01-31 发布日期:2017-02-17

Kinetics on the Extraction of Panax notoginseng

WANG Bo-ran1,2,ZHANG Wen-sheng2,ZHAO Wan-shun2,YE Zheng-liang3*   

  1. 1 Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;2 Tasly Pharmaceutical Group Company Limited,Tianjin 300410,China;  3 Tasly Holding Group Company Limited,Tianjin 300410,China
  • Online:2017-01-31 Published:2017-02-17

摘要: 研究三七的提取动力学。以Fick第一扩散定律为基础建立三七中三七皂苷R1、人参皂苷Rg1、人参皂苷Rb1三种成分的提取动力学模型,根据方程计算获得提取速率常数、表观活化能、相对萃余率等一系列动力学参数。结果表明,温度升高,三种成分提取速率加快,提取浓度升高,且温度降低各成分浓度达平衡所需时间延长。本研究所建立的三七中三种成分的提取动力学模型均符合一级动力学方程特征,该模型较好的描述了三七药材各成分的动态溶出过程,以期为三七及复方丹参提取工艺的设计和优化提供理论依据。

关键词: 三七, 提取, 动力学模型, 动力学参数

Abstract: To study kinetics on the extraction of Panax notoginseng. According to Fick’s first law of diffusion,the kinetic equations for the extraction process of PNS R1,ginsenoside Rg1,ginsenoside Rb1 were established with plate model,and the parameters,such as K(rate constant),Ea(activation energy),y (yield) were gained.The results showed that the extraction’s speed and concentration increased with the increasing of temperature,and with lower temperature,the concentration of balance time for each component became shorter.The kinetic models were accorded with characteristics of the first kinetic equation and can describe the extraction process of three ingredients of Panax notoginseng and provide the valuable theory basis for technical design.

Key words: Panax notoginseng, extraction, kinetic model, kinetic parameter

中图分类号: 

R284.1