天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (增刊1): 143-151.doi: 10.16333/j.1001-6880.2019.S.025

• 综述 • 上一篇    下一篇

钩枝藤的化学成分及药理作用研究进展

李珂珂,弓晓杰*   

  1. 大连民族大学生命科学学院,大连116600
  • 出版日期:2019-08-06 发布日期:2019-08-06
  • 基金资助:

    国家自然科学基金(81603272);大连市高层次人才创新支持计划(2017RQ152);辽宁省高等学校创新团队支持计划(LT2016017);大连市科技创新基金(2018 J12SN062);大连市第二批领军人才资助项目

Studies progress on chemical constituents of Ancistrocladus tectorius and its pharmacological activites

LI Ke-ke,GONG Xiao-jie*   

  1. Life Science College of Dalian Minzu University,Dalian 116600,China
  • Online:2019-08-06 Published:2019-08-06

摘要: 钩枝藤为产于我国海南岛的黎族民间常用药,主要含有萘基异喹啉类生物碱、黄酮类、木脂素类、香豆素类等多种化学成分,具有抗疟、抗肿瘤、杀虫、抗菌等药理活性。典型的生物碱类化学成分结构及其显著的活性作用,使钩枝藤较早引起国内外学者的广泛关注。本文对钩枝藤中化学成分及其药理作用进行综述,以期为深度开发及应用提供参考。

关键词: 钩枝藤, 萘基异喹啉生物碱, 抗疟, 抗肿瘤

Abstract: Ancistrocladus tectorius is a folk natural drug used by Li nationality in Hainan Island,China.It mainly contains naphthylisoquinoline alkaloids,flavonoids,lignans,coumarins and other chemical components.Its pharmacological activities are anti-malarial,anti-tumor,insecticidal,anti-bacterial and so on.The typical chemical structure of alkaloids composition in A.tectorius and its significant activities attract much more attention of scholars earlier both at home and abroad.In this study,the chemical constituents and pharmacological activities of A.tectorius are reviewed in order to provide a reference for the further development and rational utilization of this plant resource.

Key words: Ancistrocladus tectorius, naphthylisoquinoline, antimalarial, antitumor

中图分类号: 

R961