The fingerprint of Cinnamomi Cortex was established by ultra high performance liquid chromatography (UPLC) and the common peaks were identified.The cluster analysis (CA) and principal component analysis (PCA) of 28 batches of samples were carried out by OriginPro 2023 software.The classification of samples and common peaks of CA is similar to that of PCA,among which the sample classification of Yangchun City,Gaoyao District of Zhaoqing City,Fangchenggang City and Guigang City is more concentrated.Orthogonal partial least squares-discriminant analysis (OPLS-DA) was carried out by using SIMCA14.1 software,which can effectively distinguish Cinnamomi Cortex from Guangdong and Guangxi provinces.The samples of Cinnamomi Cortex before and after processing were compared and analyzed by determining the content of coumarin,cinnamyl alcohol,cinnamic acid,cinnamaldehyde,2-methoxycinnamaldehyde and volatile oil.The results showed that the average content of five components and volatile oil between medicinal materials and decoction pieces were similar,and there was little difference in the composition of Cinnamomi Cortex in the processing process.The overall change trends of cinnamaldehyde,cinnamic acid and cinnamyl alcohol were similar,and the changes of 2-methoxycinnamaldehyde and coumarin were similar,which were consistent with the results of chemometrics analysis.This study can provide reference for the selection of origins and quality research of Cinnamomi Cortex.