NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2022, Vol. 34 ›› Issue (增刊1): 142-157.doi: 10.16333/j.1001-6880.2022.S.020

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Research progress on chemical constituents of Polyporus fungi and their pharmacological activities

CAO Su-qin1,FANG Lei2,ZHOU Jie 2 *,ZHANG Yong-qing1   

  1. Polyporus;tetracyclic triterpenes;steroids;anti-tumor;anti-inflammatory;pharmacological activity
  • Online:2022-06-01 Published:2022-05-19

Abstract:

Polyporus (Polyporaceae) has a long history in our country.There are about 20 species,mainly distributed in Shandong,Sichuan,Hainan,Inner Mongolia and other places.It has the effects on clearing heat and detoxification,reducing swelling and throat.It has clinically been used to treat pharyngitis and tonsillitis.Polyporus fungi mainly include tetracyclic triterpenes,steroids,sesquiterpenes,aromatics and other chemical components.Among them,tetracyclic triterpenes and steroidsare rich in chemical ingredients with anti-tumor,anti-inflammatory,anti-bacterial pharmacological activities.By consulting domestic and foreign articles in the past 30 years,more than 160 compounds isolated from more than 10 kinds of Polyporus fungi were reviewed,which provides reference for further research on the chemical composition of Polyporus fungi and the rational application and development of medicinal resources.

Key words: Polyporus, tetracyclic triterpenes, steroids, anti-tumor, anti-inflammatory, pharmacological activity

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