NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2023, Vol. 35 ›› Issue (6): 1088-1099.doi: 10.16333/j.1001-6880.2023.6.018

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Biological activity of tangeretin and its potential efficacy in exercise-induced asthma:a review

LIU Meng1,2,ZHANG Zheng1,GAO Bing-hong1*,ZHOU Zhi-qin3,4   

  1. 1College of Physical Education and Training,Shanghai University of Sport,Shanghai 200438,China;2Chongqing Institute of Sport Science,Chongqing 400010,China; 3Southwest University,Chongqing 400700,China;4Southwest Institute of Fruits Nutrition,Chongqing 400054,China
  • Online:2023-06-28 Published:2023-06-28


Exercise-induced asthma (EIA) is one of the most frequent chronic diseases among athletes and is gaining increasing concern.The pathological mechanisms and pharmacology-based treatments of EIA have been widely studied and some progress has been made,however,long-term using EIA drugs would induce health-related side effects and even doping violations.Thus,a safe,healthy and effective alternative of traditional treatment methods is particularly required.Tangeretin extracted from a natural citrus was recently reported to show great promise in EIA treatment.Therefore,the current article specifically reviewed the biological activities of tangeretin referring to anti-inflammatory,antioxidant,anti-cancer,regulation of uric acid and cortisol secretion,regulation of glucolipid metabolism and anti-obesity,neuroprotection.It would provide ideas and theoretical support for further studying and developing tangeretin-based food,healthcare products or drugs in EIA treatment.

Key words: tangeretin,exercise-induced asthma,biological activity,anti-inflammatory,anti-oxidation

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