Abstract: Lead and its compounds in the environment could enter into the body through the food or respiratory system,which affect the nervous system,digestive system,hematopoietic system,and cause health problems.The antagonistic and complexation are the two main mechanisms of the lead discharging functional compound used widely.And more and more studies have focused on the natural active compounds which showed lead discharging effect,and become a research hotspot in public health.

Key words: lead poisoning, lead discharging, natural compounds, mechanism of lead discharging