NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (Suppl): 140-144. doi: 10.16333/j.1001-6880.2015.S.034

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Optimization of Supercritical Carbon Dioxide Extraction of Notopterygium incisum Ting ex H.T.Chang Essential Oil with Response Surface Methodology

LIU Wei-gen1,2, RONG Zong-gen2, YANG Lu-cun1,3, ZHANG Zhen-dong2, LIU He-chun1,3, ZHOU Guo-ying1,3*   

  1. 1 Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810001,China; 2 Environmental Protection Bureau of Shangli County,Pingxiang 337009,China; 3 Key Laboratory of Tibetan Medicine Research,Chinese Academy of Sciences,Xining 810001,China
  • Online:2015-12-01 Published:2016-01-12

Abstract: Supercritical carbon dioxide extraction of essential oil from the rhizome and root of Notopterygium incisum Ting ex H.T.Chang was optimized by response surface methodology (RSM). Based on single factor experiments,the effects of extraction pressure,temperature and time on oil yield were determined and optimized by RSM.The results showed that the optimal extraction conditions were as follows:extraction pressure 25 MPa,extraction temperature 47 ℃,extraction time 87min.Under such conditions,the oil yield was 20.37%.

Key words: Notopterygium incisum, Essential oil, Supercritical carbon dioxide extraction, Response surface methodology

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