Abstract: To study the enrichment and purification technology of effective components from the leaves of Acanthopanax sessiliflorus by macroporous resin.Explore 7 macroporus resins by using the test of static adsorption and desorption,and optimize the process parameters.The D101 macroporous resin was found to have better adsorption and desorption.The optimum conditions for purification process were as follows:the sample concentration was 0.3 g/mL;sample volume was 7 0mL;70% ethanol with 110mL to elute.The purity rate of the obtained hyperin and chiisanoside were 88.40% and 9307%.D101 is an ideal resin for adsorption,the process can provide a certain basis on the enrichment of hyperin and chiisanoside.

Key words: macroporous resin, Acanthopanax sessiliflorus, hyperin, chiisanoside