NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2025, Vol. 37 ›› Issue (10): 1962-1973. doi: 10.16333/j.1001-6880.2025.10.017 cstr: 32307.14.1001-6880.2025.10.017

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Research progress of traditional Chinese medicine in treating vascular dementia

LUO Qin-zhe,LIAO Yu-yuan,LI Juan*,LI Shun-xiang*   

  1. School of Pharmacy,Hunan University of Chinese Medicine;Hunan Engineering Technology Research Center for Bioactive Substance Discovery of Chinese Medicine;Hunan Province Sino-US International Joint Research Center for Therapeutic Drugs of Senile Degenerative Diseases,Changsha 410208,China
  • Online:2025-10-31 Published:2025-10-30

Abstract:

Vascular dementia (VaD) is a clinical syndrome caused by cerebrovascular disease.Traditional Chinese medicine believes that VaD is related to the stagnation of Xuanfu and the deficiency of the five internal organs.Modern medicine mainly associates VaD with mechanisms such as cerebral small vessel disease,atherosclerosis,and genetic genes.In recent years,the methods of traditional Chinese medicine in the treatment of VaD,including traditional Chinese medicine compound,external treatment and integrated traditional Chinese and Western medicine treatment,have shown increasing efficacy.This article provides a theoretical basis for the clinical treatment of VaD by summarizing the regulatory mechanisms of these treatment methods.

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