天然产物研究与开发 ›› 2026, Vol. 38 ›› Issue (6): 1373-1377.doi: 10.16333/j.1001-6880.2026.6.021 cstr: 32307.14.1001-6880.2026.6.021

所属专题: No.9

• 资讯 · 动态 • 上一篇    下一篇

水母雪莲木脂素类化学成分数据集

于瑞涛1,李啟钰1,3,陈静华1,3,王苗苗1,3,于瑞雪1,2*   

  1. 1中国科学院西北高原生物研究所 青海省藏药研究重点实验室,西宁 810008;2平顶山学院,平顶山 467000;3中国科学院大学,北京 100049
  • 出版日期:2026-06-26 发布日期:2026-06-24
  • 基金资助:
    青海省中央引导地方科技发展基金(2025-ZY-014)

Dataset of lignan chemical constituents from Saussurea medusa

YU Rui-tao1,LI Qi-yu1,3,CHEN Jing-hua1,3,WANG Miao-miao1,3,YU Rui-xue1,2*   

  1. 1Qinghai Provincial Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810008,China;2Medicine College of Pingdingshan University,Pingdingshan 467000,China;3University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2026-06-26 Published:2026-06-24

摘要: 水母雪莲(Saussurea medusa Maxim.)是青藏高原地区的传统藏药,其木脂素类化合物被认为是其特征性及主要活性成分。本研究基于已发表的科研文献及专业化学数据库,系统整理了从水母雪莲中已分离鉴定的62个木脂素类化合物的基本信息,包括化合物名称、分子式、分子量。为便于研究者进行结构分析、可视化及计算模拟,本数据集提供了62个木脂素类化学成分结构数据。本数据集旨在为水母雪莲的化学成分研究、活性成分筛选、药物开发及构效关系分析等多维度研究提供便捷且可扩展的基础数据支持。

关键词: 水母雪莲, 木脂素, 数据集, 结构-活性关系

Abstract:

Saussurea medusa Maxim.is a traditional Tibetan medicinal plant native to the Qinghai-Tibet Plateau,and its lignan compounds are recognized as the characteristic and major bioactive constituents.Based on published scientific literature and specialized chemical databases,this study systematically compiled the fundamental information of 62 lignan compounds that have been isolated and identified from S. medusa,including compound names,molecular formulas,and molecular weights.To facilitate structural analysis,visualization,and computational simulation for researchers,this dataset provides structural data of the 62 lignan chemical constituents.This dataset aims to offer convenient and extensible foundational data support for multidimensional research on S. medusa,including chemical composition studies,bioactive compound screening,drug development,and structure-activity relationship analysis.

Key words: Saussurea medusa, lignans, dataset, structure-activity relationship