天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (6): 1007-1010.doi: 10.16333/j.1001-6880.2015.06.012

• 研究简报 • 上一篇    下一篇

金刚纂的化学成分及其抗HIV和抗肿瘤活性研究

李洪梅,王若菲,李蓉涛*   

  1. 昆明理工大学 生命科学与技术学院,云南昆明 650500
  • 出版日期:2015-06-30 发布日期:2015-07-10

Chemical Constituents from Euphorbia neriifolia and Their Related Anti-HIV and Anti-cancer Activities

LI Hong-mei, WANG Ruo-fei, LI Rong-tao*   

  1. Faculty of Life Science and Technology,Kunming University of Science of Technology,Kunming 650500,China
  • Online:2015-06-30 Published:2015-07-10

摘要: 从金刚纂全草中分离得到一个新的天然来源的阿替生烷型二萜,3-methyl-agallochaol C(1),以及13个已知化合物。其中,化合物4和9具有一定的抗HIV-1活性,化合物10具有一定的抗肿瘤活性。

关键词: 金刚纂, 3-methyl-agallochaol C, 抗HIV, 抗肿瘤

Abstract: Systematic investigation on the whole plant of Euphorbia neriifolia led to the isolation of a new natural atisane diterpenoid,3-methyl-agallochaol C (1),along with thirteen known compounds (2-14).Among them,compounds 4 and 9 exhibited moderate anti-HIV-1 activity,and compound 10 possessed moderate anti-cancer activity.

Key words: Euphorbia neriifolia, 3-methyl-agallochaol C;anti-HIV;anti-cancer

中图分类号: 

R284.1