Tropoloisoquinoline alkaloids (TA) and azafluoranthene alkaloids (AA) are a class of alkaloids with cyclopentadieno ［i,j］ isoquinoline parent nucleus.To date,seven TA-type and eleven AA-type compounds have been isolated and identified from plants.These compounds are predominantly distributed in plants of the families Menispermaceae and Araceae,and generally occur at low abundance.Given the good biological activities of TA and AA,domestic and foreign researchers have explored and optimized the synthesis methods and reaction conditions of AA and TA.The plant sources,chemical synthesis pathways and biological activity research progress of TA and AA are systematically summarized and analyzed in this paper,in order to provide scientific reference for the optimization of the synthetic pathway,activity mechanism research and drug development of TA and AA compounds.

"> tropoloisoquinoline alkaloid, azafluoranthene alkaloids, cyclopenta ［i,j］ isoquinoline, chemical synthesis, biological activity