NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (3): 455-458.doi: 10.16333/j.1001-6880.2015.03.017

• Article • Previous Articles     Next Articles

Anti-bacterial Activity of Chrysanthemum morifolium Ramat

SONG Lei1*,ZHAN Chun-rui1,YANG Shi-ying1,MA Wei-lin1,MA Xian1,LIU Jun-xi2   

  1. 1 Medical College of Northwest University for Nationalities,Lanzhou 730030,China;2 Key Laboratory for Natural  Medicine of Gansu Province,Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China
  • Online:2015-03-30 Published:2015-04-07

Abstract: The anti-bacterial effects of crude extracts of flower of Chrysanthemum morifolium Ramat (CMR) on common human intestinal bacteria were investigated in this study.Anti-bacterial activities of ultrasonic extracts of CMR flower were tested by agar diffusion method,and minimal inhibitory concentrations (MIC) were determined by multi-proportion dilution method.The results showed that both aqueous extract and alcohol extract showed high inhibitory effect on 7 common human intestinal bacteria,especially on Proteus vulgaris, Shigella dysenteriae and Salmonella typhi. The anti-bacterial effects of aqueous and alcohol extracts with higher concentration were significantly obvious (P<0.01) than that of lower concentration,and aqueous extract showed prominent (P<0.01) anti-bacterial effects than alcohol extract at the same concentration.Furthermore,the MIC of aqueous extract lower than that of alcohol extract for the same bacterium.

Key words: Yellow chrysanthemum, extracts, intestinal bacteria, bacteriostasis

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