Abstract: Seven compounds were isolated and purified from Evodia rutaecarpa by silica gel column chromatography,MCI columnchromatography,Sephadex (LH20),HPLC and recrystallization etc.The structures of these compounds were determined based on NMR and ESIMS spectral data,as well as comparing with previous literature data.Seven compounds were determined as limonoid (1),wuchuyuamide (2),evodiamine (3),rutaecarpin (4),dievodiamine (5),evodol (6),Evodiagenine (7).In the next step,all compounds were screened for their antimonoamine oxidase activities.Compounds 3 and 5 showed MAO inhibitory activities with IC50 values of 55 μg/mL、68 μg/mL,respectively,at the concentration of 167 μg/mL.

Key words: Fructus Evodiae, limonin, alkaloid components, monoamine oxidase inhibitors