Abstract: To study chemical constituents of Endospermum chinense, thirteen known compounds were isolated from the 95% ethanol extract of E.chinense with different chromatographic methods.Their structures were identified as pubinernoid A (1), (E)-linalool-1-oic acid (2), (6S)-dehydrovomifoliol (3), 3α-hydroxy-5,6-epoxy-7megastigmen-9-one (4), oleanolic acid (5), 3-ketooleanolic acid (6), 3-oleana 9 (11), 12-dien-28-oic acid (7), mangiferonic acid (8),altissimanin C (9), 7β-hydroxy-β-sitosterol (10), syringaresinol (11),ficusesquilignan A (12),ficusesquilignan B (13).Compounds 1-4 and 7-13 were obtained from the genus Endospermum for the first time.

Key words: Endospermum chinense, Euphorbiaceae, chemical constituents, structural identification