NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (2): 209-211.

• Article • Previous Articles     Next Articles

Studies on Chemical Constituents of Theonella swinhoei from the South China Sea

GAN Jian-hong1，2，XI Da3，YU Hao-bing2，MIN Qian1，GOU Liao1，XIE Jing1*   

  1. 1 College of food science & technology,shanghai ocean university,Shanghai Engineering Research Center of Aquatic-Product Processing &Preservation,Shanghai 201306,China;2 Department of Pharmacy,ChangzhengHospital,Second Military MediacalUniversity,Shanghai 200433,China;3 Department of Minimal Invasion,Ward 2,Eastern Hepatobiliary Surgical Hospital,Second Military Medical University,Shanghai 200438,China
  • Online:2014-02-28 Published:2014-12-12

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Abstract: Sephadex LH-20 columnchromatography,silica column chromatography and HPLC methods were used to isolate and refine compounds from sponge Theonella swinhoei from the South China Sea.The structures were identified by spectroscopic analysis and comparison with the literatures.From the n-BuOH soluble extract of Theonella swinhoei, six compounds were isolated for the first time and their structures were determined as thymidine（1），thymidine-5′-carboxylic acid methyl ester（2），thymidine-5′-carboxylic acid butyl ester（3），uracil（4），thymine（5），7,8-Dimethyl-iso-alloxazine（6）.

Key words: sponge, chemical constituents, structural identification

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