Abstract: In recent years,the researchers showed that the production of many secondary metabolites in medicinal plant is low.Some secondary metabolites can reduce side effects and not conducive to the absorption of the human body,while endophyte exist in tissues or organs of healthy plants,and plant secondary metabolites can be transformed by endophyte.Biotransformation also has mild conditions,fully effective and high rate of convergence,etc.It showed that the development and expectation of the research on the microbial transformation of plant secondary metabolites by plant endophyte.It was hoped to provide some references to the resource exploitations of the endophyte.

Key words: endophyte, transformation, elicit, plant secondary metabolites