NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (Suppl1): 19-21.

• Article • Previous Articles     Next Articles

Separation and Identification of the Chemical Constituents from the Stems of Ephedra sinica

ZHAO Wei1,2, CHE Bao-quan1, HU Qin1*   

  1. 1 Beijing Institute for Drug Control,Beijing 100035,China; 2 State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China
  • Online:2014-12-30 Published:2015-03-04

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Abstract: This study was to investigate the chemical constituents of the stems of Ephedra sinica. After the plant materials were extracted and fractionated with solvents, column chromatography over silica gel was used to isolate and purified the compounds.The structures were elucidated on the basis of 1H NMR, 13C NMR,and MS analyses and comparison with the data of literatures.Nine compounds were isolated from this plant and their structures were identified as benzoic acid(1), trans-cinnamic acid(2),p-hydroxyphenylacetin acid(3),chlorogenic acid(4),protocatechuic acid(5),adenine(6),vitexin(7),rhein(8),and p-aminophenol(9), respectively. Compounds 3,6-9 were identified from the title plant for the first time.

Key words: Ephedra sinica, chemical constituents, flavanoids, organic acids

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