Abstract: To investigate anti-fungal constituents from the twigs of Ormosia hosiei.Sixteen flavonoids were isolated and purified by column chromatography.Their structures were elucidated on the basis of physico-chemicial properties and spectral analysis as sphaerobioside (1),sissotrin (2),4′,8-dimethoxyl-7-O-β-D-glucopyranosyl isoflavone (3),ononin (4),isoprunetin-7-O-β-D-glucoside(5),rutin (6),kaempferol-3-O-β-D-rutinoside (7),kushenol O (8),7-hydroxy-4′-methoxylisoflavone-7-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (9),genistein (10),isoprunetin (11),2′,4′,5,7-tetrahydroxyisoflavone (12),daidzein (13),naringenin (14),dihydrogenistein (15) and demethylmedicarpin (16).Compounds 1-16 are obtained from O.hosiei for the first time,and compounds 1,3,4,6-9,12,15,16 are obtained from the genus of Ormosia for the first time.Compounds 2,5,and 14 showed moderate inhibitory activities to the mycelial growth of Fusarium graminearum,Fusarium oxysporumf and Fusarium solani.

Key words: Ormosia hosiei, Ormosia, flavonoids, isoflavones, anti-fungi