To study the chemical constituents of Callicarpa longifolia.The methanol extract of C. longifolia was isolated and purified by silicon,Sephadex LH-20,ODS,MCI column chromatographies,semi-preparative HPLC and recrystallization method.The structures of the compounds were identified by color reaction,physicochemical properties,nuclear magnetic resonance spectroscopy and mass spectrometry.Ten compounds,18-hydroxyferruginol (1),dehydroabietanol (2),neolupenol (3),kaempferol-3,4′,7-O-trimethylether (4),artemiin (5),5-hydroxy-7,8,3′,4′-tetramethoxyflavone (6),penduleti (7),verbascoside (8),di-(2-ethylhexyl)-phthalate (9),and dibutyl phthalate (10) were isolated from C. longifolia for the first time.The anti-inflammatory effect of compounds 1-5 and 8-10 was tested on lipopolysaccharide-stimulated RAW 264.7 macrophages.The results showed that compounds 1,2,4 and 10 had significant inhibitory effects on NO production and their IC₅₀ values were 25.2,34.6,109.6 and 104.8 μmol/L respectively.