Abstract: In order to compare the pharmacodynamics of different extraction processes of Paederia scandens in the treatment of infantilemalnutrition;we used three different extraction methods to prepare the experiment samples,which including water extraction,alcohol extraction and water decocted and ethanol precipitated extraction,and then evaluated the pharmacological effects of these extracts on infantilemalnutrition by using mice model of dietary disorder and mice model of spleen deficiency and anorexia.Results showed that all the three extracts of Paederia scandens had certain therapeutic effects on infantilemalnutrition,and the ethanol extracts showed the most significant effects.This study also showed that the alcohol extraction method could obtain higher extraction efficiency of active ingredients of Paederia scandens for the treatment of infantilemalnutrition.

Key words: Paederia scandens, spleen deficiency, infantilemalnutrition, pharmacological effects