Combination of Allicin and Adriamycin Inhibits Proliferation and Induces Apoptosis in Human Gastric SGC-7901cell

Abstract

Abstract: To evaluate the anti-tumor effect of Allicin combining with ADM on the human gastric cancer cells line SGC-7901.The apoptosis of SGC-7901 cells induced by different concentrations of allicin and ADM was applied alone or together,to gastric cancer cells SGC-7901 was analyzed by visible light,fluorescence and transmission electron microscope(TEM),agrose gel electrophoresis of DNA;Distribution of cell apoptosis was analyzed using flow cytometry.The reault show that Comparred with the control，allicin and ADM and significantly inhibited the proliferation of SGC-7901 cells.The combination of allicin and ADM was found to be more effective in inhibiting growth.

Key words: Allicin, Adriamycin, SGC-7901, cell proliferation

CLC Number:

Q291

ZHANG Xi-rui,SHAO Shu-li*,LI Feng-ying,ZHANG Wei-wei. Combination of Allicin and Adriamycin Inhibits Proliferation and Induces Apoptosis in Human Gastric SGC-7901cell[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(Suppl2): 309-312.

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Combination of Allicin and Adriamycin Inhibits Proliferation and Induces Apoptosis in Human Gastric SGC-7901cell

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