天然产物研究与开发 ›› 2023, Vol. 35 ›› Issue (增刊2): 37-45.

• 研究论文 • 上一篇    下一篇

青刺尖纯露及其组合物的酪氨酸酶抑制与抗氧化活性研究

陈   艳1,赵   颖2,4,殷小雅3,王云月1,杨立新2,4*   

  1. 1云南农业大学植物保护学院;2中国科学院昆明植物研究所 植物医生研发中心;3云南民族大学民族医药学院,昆明650201;4云南省生物多样性和传统知识研究会,昆明 650034
  • 出版日期:2023-12-28 发布日期:2023-12-11
  • 基金资助:
    国家自然科学基金(31970357);植物医生项目(E15038 12C1);云南省科技厅建设面向南亚东南亚科技创新中心专项(202203AP140007)

Study on tyrosinase inhibition and antioxidant activity of Prinsepia utilis Royle pure dew and its composition

CHEN Yan1,ZHAO Ying2,4,YIN Xiao-ya3,WANG Yun-yue1,YANG Li-xin2,4*   

  1. 1College of Plant Protection,Yunnan Agricultural University; 2 Bio-Innovation Center of Dr Plant,Kunming Institute of Botany,Chinese Academy of Sciences;3 College of Ethnic Medicine,Yunnan University for Nationalities,Kunming 650201,China;4 Center of Biodiversity and Indigenous Knowledge,Kunming 650034,China
  • Online:2023-12-28 Published:2023-12-11

摘要:

青刺(Prinsepia utilis Royle)是一种药食同源的多年生落叶灌木,青刺尖为其叶和嫩茎部位。为提升本研究对照样品(青刺果油含量0.1%)的护肤活性。采用天然药物化学与护肤活性测试的方法,对青刺尖的护肤活性进行初步研究。结果表明:最优除味工艺为料液比1∶10 g/mL、时间15 min、温度为70 ℃;提取的青刺尖纯露在除味前后、加入青刺中含有的一些活性化合物后,其抗氧化和酪氨酸酶抑制活性均有所增加,并高于对照样品。本研究初步验证了青刺尖纯露具有潜在的护肤活性,为青刺资源及相关传统知识的利用保护与传承,奠定了初步的应用基础。

关键词: 青刺, 护肤, 组合物, 酪氨酸酶抑制活性, 抗氧化活性

Abstract:

Prinsepia utilis Royle is a medicinal and edible perennial deciduous shrub.The shoot of P. utilis is its leaf and tender stem.In order to improve the skin care activities of the control sample (P. utilis oil content 0.1%) in this study.The skin care activities of P. utilis was preliminarily studied by means of natural medicinal chemistry and skin care activity test.The results showed that the optimal deodorization process was as follows:the ratio of material to liquid was 1∶10 g/mL,the time was 15 min,and the temperature was 70 °C.The antioxidant and tyrosinase inhibitory activities of the pure dew extract of P. utilis before and after deodorization and after adding some active compounds contained in P. utilis increased,and were higher than those of the control samples.This study preliminarily verified the potential skin care activity of P. utilis pure dew,and laid a preliminary application foundation for the utilization,protection and inheritance of P. utilis resources and related traditional knowledge.

Key words: Prinsepia utilis, skin care, composition, tyrosinase inhibition, antioxidant activity

中图分类号:  S58