NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (4): 562-566.doi: 10.16333/j.1001-6880.2015.04.002

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Chemical Constituents from Amoora tetrapetala

MI Cheng-neng1,2,3,MEI Wen-li2,3,ZUO Wen-jian2,3, CAI Cai-hong2,3,WANG Hao2,3,LI Shao-peng1,DAI Hao-fu2,3*   

  1. 1 Hainan University,College of Horticulture,Haikou 570228,China; 2Key Laboratory of Biology and Genetic Resources of  Tropical Crops,Ministry of Agriculture,Institute of Tropical Bioscience and Biotechnology,Chinese Academy of Tropical Agricultural Sciences; 3Hainan Key laboratory for research and development of natural products from Li folk medicine,Haikou 571101,China
  • Online:2015-04-28 Published:2015-05-08

Abstract: Fourteen compounds were isolated from the branches of Amoora tetrapetala and structurally identified by spectral analysis.The compounds were identified as 22ξ-hydroxytirucalla-7,24-dien-3,23-dione (1),dymacrin D (2),zeorin (3),α-spinasterol (4),8-hydroxy-6-methoxy-3-pentylisocoumarin (5),lichenxanthone (6),10-oxo-isodauc-3-en-15-al (7),(+)-ent-ficusol (8),3-methoxy-4-hydroxybenzoate (9),vanillin (10),methyl 2,4-hydroxy-3,6-dimethylbenzoate (11),methyl 2-hydroxy-4-methoxy6-propylbenzoate (12),methyl 2,4-dihydroxy-6-methylbenzoate (13) and methyl hydrogen succinate (14).All the compounds were isolated from this genus for the first time.All chemical constituents were tested for acetylcholinesterase inhibitory activity using the Ellman colorinetric method.The results indicated that compound 11 exhibited inhibitory activity against acetylcholinesterase.

Key words: Amoora tetrapetala, chemical constituents, acetylcholinesterase inhibitory activity

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