NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (6): 1086-1091.doi: 10.16333/j.1001-6880.2015.06.027

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Anti-inflammatory,Analgesic and Hemostasis Activities of Different Extracting Fractions of Blumea balsamifera Residue

XIA Yan,LI Xiang,CHEN Jian-wei*   

  1. College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing,210023,China
  • Online:2015-06-30 Published:2015-07-10

Abstract: The objective of this study was to investigate the analgesic,anti-inflammatory and hemostasis effects of different components from Blumea balsamifera (L.) DC. residue.Anti-inflammatory effects were assessed by the weight of carrageenan-induced hind paw edema after the successive intragastric administration,the protein transudation and PEG-2 contents in the tissue were also measured.Analgesic experiments were assessed by hot-plate test.Coagulation time was tested by the slice method.The results showed that water extract of B.balsamifera showed the bestacitivity.The high dose (92 mg/kg) of water extract can lighten swelling degree by 64.04% and shorten the bleeding time.In total,different components of B.balsamifera residue hadanalgesic,anti-inflammatory and hemostasis effects.

Key words: Blumea balsamifera (L.) DC., residues, analgesia, anti-inflammatory, hemostasis

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