NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (1): 34-39. doi: 10.16333/j.1001-6880.2017.1.006

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Crude Polysaccharides Extracted from Three Characteristic Plants in Qinghai Province and Their Activities

ZHANG Qing-lin1,GAO Hui-qin1,LING Li-jun1,JI Chong-min2*,LU Yan1*,CHEN Dao-feng1   

  1. 1 School of Pharmacy,Fudan University,Shanghai 201203,China; 2 Qinghai Bozhi Biotechnology Ltd.,Xining 810000,China
  • Online:2017-01-31 Published:2017-02-17

Abstract: The crude polysaccharides were extracted from the fruits of Lyciumbar barum L., L.ruthenicum Murr.and Nitrariasibirica Pall.,collected from Qinghai,by water extraction and ethanol precipitation.The three polysaccharides had relative molecular weight distribution of 130000 to 2350000,and all were composed of mannose,rhamnose,glucuronic acid,galacturonic acid,glucose,galactose,xylose and arabinose.However,the polysaccharides were quite different on their contents of galacturonic acid,glucose and arabinose,as well as the contents of uronic acid and protein.DPPH assay indicated that the polysaccharides of N.sibirica had more potent DPPH radical scavenging activity than those of L.ruthenicum and L.barbarum,with the IC50 value of 0.19 mg/mL.Besides,all the three crude polysaccharides dramatically promoted the NO secretion of macrophage,indicating that they had immuno-enhancing activity.

Key words: Lycium chinense, Lycium ruthenicum, Nitraria sibirica, polysaccharides, anti-oxidant, immuno-enhancing

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