NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (9): 1617-1620.doi: 10.16333/j.1001-6880.2017.9.027

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Review on Structural Modifications, Biological Activities and Structure-Activity Relationships of Parthenolide

ZHANG Lei, CHEN Fan, WANG Jing*   

  1. School of Pharmacy, Zunyi Medical College, Zunyi 563003, China
  • Online:2017-09-27 Published:2017-09-27

Abstract: Parthenolide is a sesquiterpene lactone isolated from various natural plants and has lots of biological activities.In recent years,a wide range of parthenolide derivatives have been synthesized by structural modifications with valuable activities.In this review,we will highlight the advances in structural modifications,biological activities and structure-activity relationships of parthenolide.

Key words: parthenolide, structural modification, biological activity, structure-activity relationship

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