NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2019, Vol. 31 ›› Issue (12): 2098-2104.doi: 10.16333/j.1001-6880.2019.12.013

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Study on the effect of concentrations of anthraquinone derivatives detected in different thickness and drying temperature of the Rheum tanguticum Maxim. ex Balf.

LIU He-chun1,2,YAO Xiao-bo2,LEI Xue-ping2,ZHOU Guo-ying1,3 *, NIE Xiu-qing1,3,XIONG Feng1,3   

  1. 1Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810008,China;2Tibet Academy of Agriculture and Animal Husbandry Sciences,Lasa 850032,China; 3 Qinghai Key Laboratory of Qinghai-Tibet Plateau Biological Resources,Xining 810008,China
  • Online:2019-12-28 Published:2020-01-10

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Abstract: The aim was to carry out a study about the effect of concentrations of anthraquinone derivatives detected in different thickness of the Rheum tanguticum Maxim. ex Balf. by using high-performance liquid chromatography-photodiode array detector (HPLC-DAD).The condition was Column Agilent Eclipse plus C18(4.6×250 mm,5 μm) with the mobile phase consisting of methanol (A) and 0.1% acetic acid (B) in a gradient elution mode.The column temperature was 25 ℃ and the detection wavelength was 254 nm.The results showed that 75 ℃ drying,sliced 0.4-2 cm or 6-7 cm or 50 and 25 ℃ drying,sliced 0.4-3 cm or 6-8 cm,concentrations of anthraquinone derivatives detected in different thickness of the Rheum tanguticum Maxim. ex Balf. were higher,the contents were lower for other thickness,the contents of aloe-emodin,rhein,emodin,emodin,chrysophanol were in line with the above rules.To guarantee the quality of Rheum tanguticum Maxim. ex Balf.,the proposed primary processing of Rheum tanguticum Maxim. ex Balf. was:dried at 75 ℃ drying,sliced 0.4-2 cm or 6-7 cm or 50 and 25 ℃ drying,sliced 0.4-3 cm or 6-8 cm.

Key words: Rheum tanguticum Maxim. ex Balf.；HPLC-DAD, different thickness；drying temperature, anthraquinone derivatives

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