NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2019, Vol. 31 ›› Issue (11): 2007-2014.doi: 10.16333/j.10016880.2019.11.022

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Study profile on coculture of synthetic microbial community

ZHANG Xin1,LIANG Jiandong1*,TIAN Weiyi1,LIANG Zongqi2   

  1. 1College of Basic Medicine,GuiZhou University of Traditional Chinese Medicine;2 Institute of Fungus Resources,Guizhou University,Guiyang,550025,China
  • Online:2019-11-28 Published:2019-12-16

Abstract: Coculture of synthetic microbial community was a method of culturing two or more microorganisms together in a culture container,Through the simulation of natural ecology,to build artificial microbial community,it could lead to an increase in the accumulation of existing natural products,or trigger the expression of silenced biosynthesis pathways due to microbial crosstalk and chemical defense to produce new compounds.This review introduced the coculture system and application of synthetic microbial community,worth further studying and exploring.

Key words: coculture, synthetic microbial community, fermentation, metabolomics

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