The Research on Chemical Ingredients of the Heartwood of Root of Morus atpropurpurea

Abstract

Abstract: Eight known compounds,including Moracin C(1),Moracin M(2),Dihydromorin(3),Oxyresveratrol(4),2,4-Dihydroxybenzaldehyde(5),7-Hydroxycoumarin(6),Daucosterol(7) and 3-Hydroxy-2-piperidinone(8)have been isolated from EtOH extract of heartwood of root of Morus atpropurpurea.Compounds 1,3-6 and 8 were isolated from Morus atpropurpurea for the first time.Compound 8 was also isolated from Morus plant for the first time.Their antioxidant and neuroprotective activity were test by DPPH,MTT methods.Polyphenolic compounds 1-4 exhibited antioxidative and neuroprotective activitives.Compound 2 showed significant neuroprotective activity at 20 μM.

Key words: Morus atpropurpurea, heartwood, chemical ingredients, neuroprotection, antioxidation

CLC Number:

O629.9

HE Xi-xin1*, CHAO Xiao-juan2,YANG Lu1, ZHANG Cui-xian1, PI Rong-biao2, ZENG Hai-xiang1, LI Guo-xi1, XU Yu-juan1,LIN Yan-yan1. The Research on Chemical Ingredients of the Heartwood of Root of Morus atpropurpurea[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(2): 193-196.

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The Research on Chemical Ingredients of the Heartwood of Root of Morus atpropurpurea

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