Isolation，Purification and α-Glucosidase Inhibitory Ability of Triterpenes from the Fruits of Terminalia Chebula Retz.

Abstract

Abstract: In order to recognize α-glucosidase inhibitory ability of triterpenes from the fruits of T.Chebula Retz,the trierpentes were isolated and purified by TLC-guide method and the bioactivity in vitro was investigated by means of the inhibitory activity against to α-Glucosidase combined with HPLC.Three compounds were obtained from the acetic ether extract and identified as arjunic acid,arjunolic acid,arjungenin,among them,arjunic acid (IC₅₀= 2.97 μmol/mL) and arjunolic acid (IC₅₀= 0.82 μmol/mL) had theability against to α-glucosidase.

Key words: Terminalia chebula Retz., α-Glucosidase;HPLC;arjunic acid;arjunolic acid

CLC Number:

R932

YANG Lan-ping1,ZHU Jing-bo1,2*,DING Yan1,WANG Zhen-zhong3, XIAO Wei3. Isolation，Purification and α-Glucosidase Inhibitory Ability of Triterpenes from the Fruits of Terminalia Chebula Retz.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(Suppl2): 194-196.

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Isolation，Purification and α-Glucosidase Inhibitory Ability of Triterpenes from the Fruits of Terminalia Chebula Retz.

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