天然产物研究与开发 ›› 2026, Vol. 38 ›› Issue (3): 662-678.doi: 10.16333/j.1001-6880.2026.3.022 cstr: 32307.14.1001-6880.2026.3.022

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链格孢属真菌中有开发潜力的活性次级代谢产物研究进展 

秦飞飞*,张  婕   

  1. 呼伦贝尔学院农学院,呼伦贝尔 021008
  • 出版日期:2026-03-27 发布日期:2026-03-26
  • 基金资助:
    内蒙古自治区自然科学基金(2021BS03029);呼伦贝尔学院自然科学重点项目(2021ZKZD02)

Research progress of active secondary metabolites with exploitation potential from Alternaria sp.

QIN Fei-fei *, ZHANG Jie   

  1. School of Agriculture,Hulunbuir University,Hulunbuir 021008,China
  • Online:2026-03-27 Published:2026-03-26

摘要:

链格孢(Alternaria sp.)是一类自然界中最常见的真菌,其种类繁多,分布广泛。虽然链格孢作为病原真菌,对经济造成严重损失的同时,还对人类健康造成了不利的影响,但其极强的次生代谢能力,可产生具有抗虫、抗菌和抗肿瘤等活性的次级代谢产物,有些产物甚至可以除草和抑制海洋浮游生物的生长,因此链格孢属真菌的次级代谢产物具有巨大的开发利用价值。本文总结了2013年至2023年链格孢属真菌产生的128个可进一步开发利用的物质,并将所有代谢产物的化学结构和生物活性进行了系统的总结,以期为链格孢属真菌次级代谢产物的进一步发掘和开发利用提供科学依据。

关键词: 链格孢, 活性次级代谢产物, 开发利用

Abstract:

Alternaria sp. is one of the most common fungi in nature, with a wide variety of species and wide distribution. As pathogenic fungi, Alternaria not only cause serious economic losses but also have adverse effects on human health. However, its strong secondary metabolic capacity can produce metabolites with activities such as insect resistance, antibacterial and anti-tumor. Some products can even control weed and inhibit the growth of marine plankton. So the secondary metabolites of Alternaria have great potential research and development value. This article summarizes 128 secondary metabolites produced by Alternaria from 2013 to 2023 that can be further developed and utilized, and systematically summarizes the chemical structures and biological activities of all metabolites, in order to provide scientific basis for further development and utilization of secondary metabolites of Alternaria.

Key words: Alternaria, Active secondary metabolites, development and utilization

中图分类号:  Q936