椰子种皮油提取物对低密度脂蛋白氧化的抑制作用

doi:A

天然产物研究与开发 ›› 2012, Vol. 24 ›› Issue (5): 668-671.doi: A

椰子种皮油提取物对低密度脂蛋白氧化的抑制作用

赵晓莉^1,2，陈卫军^2*，赵松林²，张春梅²，王妨¹

¹海南大学食品学院，海口 570228；²中国热带农业科学院椰子研究所产品加工研究室，文昌 571339

收稿日期:2011-06-08 出版日期:2012-05-25 发布日期:2012-06-12
基金资助:
公益性行业（农业）科研专项经费项目（200903026-3）；海南省社会发展科技专项（2010SF006）

Inhibition of Coconut Testa Oil Extracts on Human Low-density Lipoprotein Oxidation

ZHAO Xiao-li¹, CHEN Wei-jun^2*, ZHAO Song-lin², ZHANG Chun-mei², WANG Fang¹

¹College of Food, Hainan University, Haikou 570228, China; ²Coconut Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wenchang 571339, China

Received:2011-06-08 Online:2012-05-25 Published:2012-06-12

摘要/Abstract

摘要： 本文研究了椰子种皮油提取物对低密度脂蛋白氧化的抑制作用，以水溶性VE（Trolox）作为对照，测定椰子种皮油提取物的总酚含量，总抗氧化能力，检测提取物对低密度脂蛋白的氧化易感性，硫代巴比妥酸反应产物（TBARS）值及铜络合能力的影响。结果表明，椰子种皮油提取物的总酚含量为68.6 mg/g，总抗氧化能力也随着浓度增大而加强，说明该提取物具有较好的抗氧化活性。浓度为0.5 mg/mL的提取物能将低密度脂蛋白的延滞时间延长了两倍，丙二醛（MDA）含量也明显下降，表明椰子种皮油提取物对低密度脂蛋白的氧化具有一定的抑制作用。

关键词: 椰子种皮油提取物, 低密度脂蛋白, TBARS, 脂质过氧化, 铜络合

Abstract: The inhibition activity of coconut testa oil extracts on human low density lipoprotein (LDL) was investigated by comparing with Trolox. Assays of copper-mediated LDL oxidation, thiobarbituric acid-reactive substances (TBARS) formation, total antioxidant capacity, total phenolic content and Cu2+ binding studies were carried out in this paper. The results showed that the extracts of coconut testa oil had the evident inhibition effect on low density lipoprotein oxidation. The total phenolic content was 68.6 mg/100 g. And 100 μL extract at 0.5 mg/mL could increase the lag time to 41 min, but evidently decrease the value of TBARS.

Key words: coconut testa oil extracts, LDL, TBARS, lipid peroxidation, Cu2+ binding

中图分类号: TS222+.1

赵晓莉，陈卫军,赵松林，张春梅，王妨. 椰子种皮油提取物对低密度脂蛋白氧化的抑制作用[J]. 天然产物研究与开发, 2012, 24(5): 668-671.

ZHAO Xiao-li, CHEN Wei-jun, ZHAO Song-lin, ZHANG Chun-mei, WANG Fang. Inhibition of Coconut Testa Oil Extracts on Human Low-density Lipoprotein Oxidation[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 24(5): 668-671.

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椰子种皮油提取物对低密度脂蛋白氧化的抑制作用

Inhibition of Coconut Testa Oil Extracts on Human Low-density Lipoprotein Oxidation

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