天然产物研究与开发 ›› 2026, Vol. 38 ›› Issue (8): 1849-1856.doi: 10.16333/j.1001-6880.2026.8.022 cstr: 32307.14.1001-6880.2026.8.022

• 综述 • 上一篇    下一篇

组学技术在党参质量评价及药理作用机制研究中的应用

姚昱吏,南丹慧,康荣峰,杨扶德*   

  1. 甘肃中医药大学,兰州 730000
  • 出版日期:2026-08-27 发布日期:2026-08-26
  • 基金资助:
    中药材及饮片质量控制重点实验室(2024GSMPA-KL);2021年度甘肃高等学校产业支撑计划(2021CYZC-40);甘肃省重点研发计划(23YFFA0069)

Application of omics technology in quality evaluation and pharmacological mechanism research of Codonopsis Radix

YAO Yu-li,NAN Dan-hui,KANG Rong-feng,YANG Fu-de*   

  1. Gansu University of Chinese Medicine,Lanzhou 730000,China
  • Online:2026-08-27 Published:2026-08-26

摘要: 党参具有健脾益肺、养血生津的功效,也是重要的药食同源植物,具有抗肿瘤、抗氧化、抗疲劳、抗炎、保肝、保胃等多种药理作用。近年来,随着党参用量的日益增加,其质量问题也愈加严重,严重影响其临床疗效与安全用药,而组学技术的提出为党参研究提供了新的思路。鉴于此,本文对组学技术在中药党参质量评价及药理作用机制研究中的应用进行概括和综述,为今后进一步开发利用党参资源、对党参进行深入研究提出新的见解。

关键词: 组学技术, 党参, 质量评价, 药理作用, 机制

Abstract:

Codonopsis Radix has the effects of invigorating the spleen and lung,nourishing blood and promoting the production of body fluid.It is also an important plant that can be used both as food and medicine and has a variety of pharmacological effects such as anti-tumor,anti-oxidation,anti-fatigue,anti-inflammation,liver protection and stomach protection.In recent years,with the increasing use of Codonopsis Radix,its quality problems have become more and more serious,which seriously affects its clinical efficacy and safe medication.The emergence of omics technology provides a new idea for the research of Codonopsis Radix.In view of this,this paper summarizes and reviews the application of omics technology in the quality evaluation and pharmacological mechanism research of Codonopsis Radix,and puts forward new insights for the further development and utilization of Codonopsis Radix resources and in-depth research on Codonopsis Radix in the future.

Key words: omics technology, Codonopsis Radix, quality evaluation, pharmacological action, mechanism

中图分类号:  R932