A New Triterpenoid from Maytenus austroyunnanensis

doi:10.16333/j.1001-6880.2016.2.001

Abstract

Abstract: In this study the method of anti-tumor activity tracking was used to screen active components from Maytenus austroyunnanensis.As a result,eight triterpenoids were isolated and identified respectively as:19α-hydroxy-3-oxo-olean-12-en-29-oic acid (1),22β-hydroxy-3-oxo-olean-12-en-29-oic acid (2),3β-hydroxy-22-oxo-olean-12-en-29-oic acid (3),3β-hydroxy-olean-12-en-29-oic acid (4),3β,22β-dihydroxy-olean-12-en-29-oic acid (5),3α,22α-dihydroxy-olean12-en-29-oic acid (6),3β,22α-dihydroxy-olean-12-en-29-oic acid (maytenfolic acid) (7),3α,22β-dihydroxy-olean-12-en-29-oic acid (8) by means of spectroscopic methods.Compound 1 was a new compound.Compounds 1,2,4,6 showed significant cytotoxic activity against HeLa cells.

Key words: Maytenus austroyunnanensis, anti-tumor activity, triterpenoids

CLC Number:

R284.1

TAN Wen-zhuang,PU De-bing,FENG Yang,LI Hai-zhou*. A New Triterpenoid from Maytenus austroyunnanensis[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(2): 173-178.

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A New Triterpenoid from Maytenus austroyunnanensis

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