Endophytic fungi live in the plant tissue and coexists with the plan.The secondary metabolites of plant endophytic fungi have the characteristics of structure and bioactive diversity,so they can provide a leading structure for the creation of medicine and pesticides,and have great research and development value.In this paper,the biologically active alkaloids,polyketones,terpenes,sterols,anthraquinones,and other compounds isolated from plant endophytic fungi in recent three years (2017-2019) were reviewed,and the research progress of their bioactivity was briefly summarized,in order to provide reference for the research and utilization of the bioactive metabolites of endophytic fungi.