NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2020, Vol. 32 ›› Issue (9): 1621-1627.doi: 10.16333/j.1001-6880.2020.9.022

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Advance in the separation and preparation of natural products for ionic liquids by high-speed counter-current chromatography

ZHANG Xia1,2,HUANG Xin-yi1,2,HAO Quan3,DI Duo-long1,2*#br#


  1. 1CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China;2University of Chinese Academy of Sciences,Beijing 100049,China;3Lanzhou Foci Pharmaceutical Co.,Ltd.,Lanzhou 730000,China

  • Online:2020-09-28 Published:2020-09-25


Ionic liquids are widely used in separation and analysis of natural products in recent years.This review mainly focuses on the research progress of ionic liquids in separation and analysis of natural products by high-speed counter-current chromatography.Especially,as a two-phase solvent modifier for high-speed counter-current chromatography,there are detailed introductions of application and development for ionic liquids used in separation and preparation of natural products.Meanwhile,the future development direction of ionic liquids is also prospected in this review.

Key words: ionic liquids, high-speed counter-current chromatography, natural products, solvent modifiers

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